In genetic terms, yes — Indigenous peoples of the Americas (often historically labeled “Amerindians”) descend mainly from ancient Northeast Asian–related populations, not from today’s East Asian national groups as a simple one-to-one match. Ancient DNA shows a founding population that split from East Asian-related ancestors tens of thousands of years ago, with additional Ancient North Siberian ancestry, then diversified in or near Beringia before spreading into the Americas.
A Nature study of an ~11,500-year-old Ancient Beringian genome from Alaska (Upward Sun River) found that Ancient Beringians and other Native American ancestors came from a single founding population that separated from East Asians around 36,000 years ago, with later structure and southward diversification. Later Asian gene flow also contributed especially to some Arctic and Na-Dene groups, so the story is shared deep ancestry plus later complexity — not identity with modern Chinese, Japanese, or Korean populations.
Source: Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans — Nature