Yes. Bullhead catfish are edible freshwater fish. The U.S. Food and Drug Administration’s Seafood List lists brown bullhead (Ameiurus nebulosus) with acceptable market names of Bullhead or Catfish, and it likewise lists black and yellow bullhead species under those market names.
Like other fish, wild-caught bullheads can pick up contaminants from the waters they live in, so anglers should follow local fish-consumption advisories. The FDA entry also carries a hazard-information flag (HAZ), which means processors should apply standard seafood food-safety controls—not that the fish is poisonous to eat.
Source: Brown bullhead (Ameiurus nebulosus) — FDA The Seafood List