No. In literature, a protagonist is the principal character whose goals and choices drive the story; an antagonist is the main opposing person, group, or force that blocks those goals. The two roles are defined by conflict, not by moral labels: the antagonist is an opponent, not necessarily a villain.
Britannica describes the protagonist as the principal character in a novel, story, or drama (originally the leading actor in Greek tragedy). Literary Devices defines an antagonist as a character, group, or other force in direct conflict with the protagonist—someone or something that tries to stop the protagonist from getting what they want. That opposing force can be another person, an institution, nature, society, or even a flaw within the protagonist.
Source: Encyclopaedia Britannica — Protagonist; see also Literary Devices — Antagonist