Yes. California is home to seven rattlesnake species, which live in habitats from the coast to inland deserts and from near sea level to thousands of feet in elevation.
According to the California Department of Fish and Wildlife, the western rattlesnake (Crotalus oreganus) is the most widespread and occurs statewide up to about 7,000 feet, while species such as the sidewinder, Mohave, red diamond, speckled, Panamint, and western diamond-backed rattlesnakes are mainly found in southern or desert parts of the state.
Source: California Department of Fish and Wildlife — Rattlesnake