Yes. Researchers at Maynooth University in Ireland described a Scaffolded DNA Computer (SDC) in Nature on September 16, 2026, that uses self-assembling DNA strands in water and salt to run programmed calculations without continuous electricity—only heat to start the reactions. The system executed 10 molecular programs, including multiplication, division, and addition of 25-bit numbers (a 100-bit computation), by letting DNA base-pair binding settle into a thermodynamically favoured answer structure.
September 19 coverage explained the build uses DNA origami–style scaffolding: a long scaffold strand plus short “staple” strands that fold into a microscopic computing grid when heated and cooled.
Source: Tom’s Hardware coverage of the Maynooth University / Nature Scaffolded DNA Computer (citing Nature, Sept. 16, 2026).